This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MDFIC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-99 amino acids from the N-terminal region of human MDFIC.
HIC antikoerper, Kdt1 antikoerper, Mdfid antikoerper, MyoD family inhibitor domain containing antikoerper, MyoD family inhibitor domain containing S homeolog antikoerper, MDFIC antikoerper, Mdfic antikoerper, mdfic.S antikoerper
Hintergrund
MDFIC is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus.