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Importin 11 Antikörper (N-Term)

IPO11 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB23487 unconjugated
Produktnummer ABIN652718
  • Target Alle Importin 11 (IPO11) Antikörper anzeigen
    Importin 11 (IPO11)
    Bindungsspezifität
    • 10
    • 9
    • 7
    • 7
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 56-85, N-Term
    Reaktivität
    • 46
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 46
    Kaninchen
    Klonalität
    • 45
    Polyklonal
    Konjugat
    • 22
    • 6
    • 5
    • 5
    • 4
    • 4
    Dieser Importin 11 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 32
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This IPO11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human IPO11.
    Klon
    RB23487
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    Importin 11 (IPO11)
    Andere Bezeichnung
    IPO11 (IPO11 Produkte)
    Synonyme
    MGC83107 antikoerper, IPO11 antikoerper, slrn antikoerper, ranbp11 antikoerper, RanBP11 antikoerper, 1700081H05Rik antikoerper, 2510001A17Rik antikoerper, AI314624 antikoerper, AW555235 antikoerper, E330021B14Rik antikoerper, Ranbp11 antikoerper, importin 11 S homeolog antikoerper, importin 11 antikoerper, importin-11 antikoerper, ipo11.S antikoerper, ipo11 antikoerper, IPO11 antikoerper, AFUA_1G03590 antikoerper, BDBG_04626 antikoerper, LOC100162908 antikoerper, Ipo11 antikoerper
    Hintergrund
    IPO11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). It mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).
    Molekulargewicht
    112535
    Gen-ID
    51194
    NCBI Accession
    NP_001128251, NP_057422
    UniProt
    Q9UI26
    Pathways
    Protein targeting to Nucleus
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