CTPS2 Antikörper (N-Term)

Produktnummer ABIN652725

Produktdetails anti-CTPS2 Antikörper

Target: CTPS2 (CTP Synthase II (CTPS2))

Bindungsspezifität: AA 77-105, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTPS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Homologie: B, M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the N-terminal region of human CTPS2.

Klon: RB23574

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CTPS2

Target: CTPS2 (CTP Synthase II (CTPS2))

Andere Bezeichnung: CTPS2 (CTPS2 Produkte)

Synonyme: A830031M15Rik antikoerper, AI326475 antikoerper, Ctpsh antikoerper, CTP synthase 2 L homeolog antikoerper, CTP synthase 2 antikoerper, cytidine 5'-triphosphate synthase 2 antikoerper, ctps2.L antikoerper, CTPS2 antikoerper, ctps2 antikoerper, Ctps2 antikoerper

Hintergrund: CTPS2 catalyzes the formation of CTP from UTP with the concomitant eamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy.

Molekulargewicht: 65678

Gen-ID: 56474

NCBI Accession: NP_001137474, NP_062831, NP_787055

UniProt: Q9NRF8

Pathways: Ribonucleoside Biosynthetic Process