Glutaminase Antikörper (C-Term)
(1 reference)-
- Target Alle Glutaminase (GLS) Antikörper anzeigen
- Glutaminase (GLS)
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Bindungsspezifität
- AA 516-545, C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Glutaminase Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This GLS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-545 amino acids from the C-terminal region of human GLS.
- Klon
- RB22875
- Isotyp
- Ig Fraction
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anti-Glutaminase (GLS) (AA 31-253) antibody
GLS Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Glutaminase (GLS) (AA 580-669) antibodyGLS Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 5C4 unconjugated
anti-Glutaminase (GLS) (AA 610-669) antibodyGLS Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Glutaminase (GLS) (AA 221-533) antibodyGLS Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Glutaminase (GLS) antibodyMicroarray verified GLS Reaktivität: Human, Maus IHC Wirt: Maus Monoclonal MAB601157 unconjugated
anti-Glutaminase (GLS) (C-Term) antibodyGLS Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
anti-Glutaminase (GLS) (AA 616-669) antibodyGLS Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Glutaminase (GLS) (AA 580-669) antibodyGLS Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Glutaminase (GLS) (AA 555-587) antibodyGLS Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB53877 unconjugated
anti-Glutaminase (GLS) (AA 144-177) antibodyGLS Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB53876 unconjugated
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- Applikationshinweise
- WB: 1:1000. WB: 1:1000. IF: 1:25. IF: 1:25. IF: 1:25. WB: 1:1000. WB: 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid freeze-thaw cycles.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
- Haltbarkeit
- 6 months
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-
: "The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy." in: Nature communications, Vol. 7, pp. 11321, (2016) (PubMed).
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: "The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy." in: Nature communications, Vol. 7, pp. 11321, (2016) (PubMed).
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- Target
- Glutaminase (GLS)
- Andere Bezeichnung
- GLS (GLS Produkte)
- Hintergrund
- Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter(Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.
- Molekulargewicht
- 73461
- Gen-ID
- 2744
- NCBI Accession
- NP_001243239, NP_055720
- UniProt
- O94925
- Pathways
- Feeding Behaviour, Dicarboxylic Acid Transport, Warburg Effekt
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