LDLR Antikörper (AA 391-419)
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- Target Alle LDLR Antikörper anzeigen
- LDLR (Low Density Lipoprotein Receptor (LDLR))
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Bindungsspezifität
- AA 391-419
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LDLR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Homologie
- X, B, Ha, Pig, Rb, Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This LDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids of human LDLR.
- Klon
- RB22886
- Isotyp
- Ig Fraction
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anti-Low Density Lipoprotein Receptor (LDLR) (AA 391-419) antibodyLDLR Reaktivität: Human, Maus WB, FACS Wirt: Kaninchen Polyclonal RB22886 unconjugated
anti-Low Density Lipoprotein Receptor (LDLR) (AA 499-511) antibodyLDLR Reaktivität: Human, Maus WB, IHC, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:1000. FC: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- LDLR (Low Density Lipoprotein Receptor (LDLR))
- Andere Bezeichnung
- LDLR (LDLR Produkte)
- Hintergrund
- The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.
- Molekulargewicht
- 95376
- Gen-ID
- 3949
- NCBI Accession
- NP_000518, NP_001182727, NP_001182728, NP_001182729, NP_001182732
- UniProt
- P01130
- Pathways
- Hepatitis C, Lipid Metabolism
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