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PKM2 Antikörper (N-Term)

Name: PKM2 Antikörper (N-Term)
SKU: ABIN653018
Price: 445.5 EUR
Availability: InStock

PKM2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB15338 unconjugated

Western blot analysis of PKM2 (arrow) using rabbit polyclonal PKM2 Antibody (N-term ) (ABIN653018 and ABIN2842641). (PKM2 Antikörper (N-Term))

PKM2 (N-term ) Antibody (ABIN653018 and ABIN2842641) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram). (PKM2 Antikörper (N-Term))

FACS

PKM2 (N-term ) Antibody (ABIN653018 and ABIN2842641) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. (PKM2 Antikörper (N-Term))

IHC (p)

3 Abbildungen

Produktnummer ABIN653018

Datenblatt (PDF)

Target Alle PKM2 Antikörper anzeigen

PKM2 (Pyruvate Kinase M2 (PKM2))
Bindungsspezifität
21

16

16

12

7

7

7

7

7

6

6

5

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 116-145, N-Term
Reaktivität
149

105

93

4

4

2

2

2

2

2

1

1

1
Human
Wirt
127

22

5
Kaninchen
Passende Sekundärantikörper
Klonalität
133

21
Polyklonal
Konjugat
57

12

9

9

9

9

9

9

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1
Dieser PKM2 Antikörper ist unkonjugiert
Applikation
85

34

27

27

22

19

14

12

9

7

7

5

2

2

2

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie

M, Rb, Rat

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This PKM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the N-terminal region of human PKM2.

Klon

RB15338

Isotyp

Ig Fraction

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anti-Pyruvate Kinase M2 (PKM2) (AA 294-470) antibody
PKM2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 141-248) antibody
PKM2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 476-505), (C-Term) antibody
PKM2 Reaktivität: Human, Maus, Ratte, Affe WB, IHC (p), IF Wirt: Kaninchen Polyclonal RB3697 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (pTyr105) antibody
PKM2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 383-417), (C-Term) antibody
PKM2 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB18405 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 116-145) antibody
PKM2 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 476-505) antibody
PKM2 Reaktivität: Human, Maus, Ratte, Primate WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 255-350) antibody
PKM2 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 121-151), (N-Term) antibody
PKM2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB5870 unconjugated

anti-Pyruvate Kinase M2 (PKM2) (AA 1-531) antibody
PKM2 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

PKM2 (Pyruvate Kinase M2 (PKM2))

Andere Bezeichnung

PKM2 (PKM2 Produkte)

Synonyme

CTHBP antikoerper, OIP3 antikoerper, PK3 antikoerper, PKM2 antikoerper, TCB antikoerper, THBP1 antikoerper, AA414905 antikoerper, AL024370 antikoerper, AL024424 antikoerper, Pk-2 antikoerper, Pk-3 antikoerper, Pk3 antikoerper, Pkm2 antikoerper, PKM12 antikoerper, PKM antikoerper, pyruvate kinase M1/2 antikoerper, pyruvate kinase, muscle antikoerper, PKM antikoerper, Pkm antikoerper

Hintergrund

PKM2 encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

Molekulargewicht

57937

Gen-ID

5315

NCBI Accession

NP_001193725, NP_001193726, NP_001193727, NP_001193728, NP_002645, NP_872270, NP_872271

UniProt

P14618

Pathways

Warburg Effekt