CIRBP Antikörper (C-Term)

Produktnummer ABIN653083

Produktdetails anti-CIRBP Antikörper

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Bindungsspezifität: AA 145-172, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CIRBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Ha, M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CIRBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-172 amino acids from the C-terminal region of human CIRBP.

Klon: RB23135

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-CIRBP Antikörper (ABIN653083)

Chen, Ran, Xie, Xu, Zhou: "Cold-inducible RNA-binding protein mediates cold air inducible airway mucin production through TLR4/NF-κB signaling pathway." in: International immunopharmacology, Vol. 39, pp. 48-56, (2017) (PubMed).

Details zu CIRBP

Target: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Andere Bezeichnung: CIRBP (CIRBP Produkte)

Synonyme: CIRP antikoerper, Cirp antikoerper, R74941 antikoerper, Xcirp antikoerper, cirbp antikoerper, cirbp-a antikoerper, cirbp2 antikoerper, cirp antikoerper, cirp1 antikoerper, cirp2 antikoerper, xcirp2 antikoerper, XCIRP antikoerper, XCIRP-1 antikoerper, cirbp-b antikoerper, cirp-1 antikoerper, APBP-1 antikoerper, zgc:136559 antikoerper, CIRBP antikoerper, A18 hnRNP antikoerper, cold inducible RNA binding protein antikoerper, cold-inducible RNA-binding protein antikoerper, cold inducible RNA binding protein S homeolog antikoerper, cold inducible RNA binding protein L homeolog antikoerper, cold inducible RNA binding protein b antikoerper, CIRBP antikoerper, EDI_107320 antikoerper, Cirbp antikoerper, cirbp.S antikoerper, cirbp.L antikoerper, cirbp antikoerper, cirbpb antikoerper

Hintergrund: CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor (By similarity) and promotes assembly of stress granules (SGs), when overexpressed.

Molekulargewicht: 18648

Gen-ID: 1153

NCBI Accession: NP_001271

UniProt: Q14011

Pathways: Ribonucleoprotein Complex Subunit Organization