CBY1/PGEA1 Antikörper (C-Term)

Produktnummer ABIN653093

Produktdetails anti-CBY1/PGEA1 Antikörper

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Bindungsspezifität: AA 98-126, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBY1/PGEA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HRIHFB2025 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the C-terminal region of human HRIHFB2025.

Klon: RB23191

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-CBY1/PGEA1 Antikörper (ABIN653093)

Yamano, Uzawa, Saito, Nakashima, Kasamatsu, Koike, Kouzu, Shinozuka, Nakatani, Negoro, Fujita, Tanzawa: "Identification of cisplatin-resistance related genes in head and neck squamous cell carcinoma." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 2, pp. 437-49, (2009) (PubMed).

Details zu CBY1/PGEA1

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Andere Bezeichnung: HRIHFB2025 (CBY1 Produkte)

Synonyme: chibby antikoerper, cby antikoerper, arb1 antikoerper, pgea1 antikoerper, pigea14 antikoerper, pigea-14 antikoerper, hs508i15a antikoerper, C22orf2 antikoerper, CBY antikoerper, HS508I15A antikoerper, PGEA1 antikoerper, PIGEA-14 antikoerper, PIGEA14 antikoerper, 1110014P06Rik antikoerper, PGEA14 antikoerper, Pgea1 antikoerper, chibby homolog 1 S homeolog antikoerper, chibby homolog 1 antikoerper, chibby family member 1, beta catenin antagonist antikoerper, cby1.S antikoerper, cby1 antikoerper, CBY1 antikoerper, Cby1 antikoerper

Hintergrund: Inhibits the Wnt/Wingless pathway by binding to beta catenin and inhibiting beta catenin mediated transcriptional activation by competing with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin 2/PKD2 and possibly of other intracellular proteins.

Molekulargewicht: 14470

Gen-ID: 25776

NCBI Accession: NP_001002880, NP_056188

UniProt: Q9Y3M2