F-Box Protein 3 Antikörper (C-Term)

Produktnummer ABIN653142

Produktdetails anti-F-Box Protein 3 Antikörper

Target: F-Box Protein 3 (FBXO3)

Bindungsspezifität: AA 395-422, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser F-Box Protein 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FBXO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-422 amino acids from the C-terminal region of human FBXO3.

Klon: RB23911

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-F-Box Protein 3 Antikörper (ABIN653142)

Schlierf, Altmann, Quancard, Jefferson, Assenberg, Renatus, Jones, Hassiepen, Schaefer, Kiffe, Weiss, Wiesmann, Sedrani, Eder, Martoglio: "Targeted inhibition of the COP9 signalosome for treatment of cancer." in: Nature communications, Vol. 7, pp. 13166, (2018) (PubMed).

Details zu F-Box Protein 3

Target: F-Box Protein 3 (FBXO3)

Andere Bezeichnung: FBXO3 (FBXO3 Produkte)

Synonyme: FBA antikoerper, FBX3 antikoerper, 1200002G09Rik antikoerper, 1700026K02Rik antikoerper, AI046358 antikoerper, Fba antikoerper, zgc:112485 antikoerper, DKFZp459H187 antikoerper, F-box protein 3 antikoerper, F-box protein 3 S homeolog antikoerper, FBXO3 antikoerper, Fbxo3 antikoerper, fbxo3.S antikoerper, fbxo3 antikoerper

Hintergrund: FBXO3 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.

Molekulargewicht: 54561

Gen-ID: 26273

NCBI Accession: NP_036307, NP_208385

UniProt: Q9UK99