This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This RECK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-456 amino acids from the Central region of human RECK.
ST15 antikoerper, St15 antikoerper, mRECK antikoerper, reversion inducing cysteine rich protein with kazal motifs antikoerper, reversion-inducing-cysteine-rich protein with kazal motifs antikoerper, RECK antikoerper, Reck antikoerper
Hintergrund
RECK is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis.