Dieser Galanin Receptor 1 Antikörper ist unkonjugiert
Applikation
Western Blotting (WB), Flow Cytometry (FACS)
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GALR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-200 amino acids from the Central region of human GALR1.
GALR1 elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.