T-Box 1 Antikörper (C-Term)
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- Target Alle T-Box 1 (TBX1) Antikörper anzeigen
- T-Box 1 (TBX1)
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Bindungsspezifität
- AA 327-356, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser T-Box 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This TBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 327-356 amino acids from the C-terminal region of human TBX1.
- Klon
- RB22154
- Isotyp
- Ig Fraction
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- Applikationshinweise
- IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:25
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- T-Box 1 (TBX1)
- Andere Bezeichnung
- TBX1 (TBX1 Produkte)
- Synonyme
- CAFS antikoerper, CTHM antikoerper, DGCR antikoerper, DGS antikoerper, DORV antikoerper, TBX1C antikoerper, TGA antikoerper, VCFS antikoerper, mp:zf637-3-000616 antikoerper, zgc:136724 antikoerper, TBX1 antikoerper, dgs antikoerper, tga antikoerper, cafs antikoerper, cthm antikoerper, dgcr antikoerper, dorv antikoerper, vcfs antikoerper, tbx1c antikoerper, xtbx1 antikoerper, tbx1 antikoerper, T-box 1 antikoerper, T-box 1 S homeolog antikoerper, T-box 1 L homeolog antikoerper, TBX1 antikoerper, Tbx1 antikoerper, tbx1 antikoerper, tbx1.S antikoerper, tbx1.L antikoerper
- Hintergrund
- TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98 % amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Molekulargewicht
- 43133
- Gen-ID
- 6899
- NCBI Accession
- NP_005983, NP_542377, NP_542378
- UniProt
- O43435
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation
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