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GSTa2 Antikörper (N-Term)

GSTa2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB24006 unconjugated
Produktnummer ABIN653362
  • Target Alle GSTa2 Antikörper anzeigen
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 2
    • 1
    • 1
    AA 1-30, N-Term
    Reaktivität
    • 38
    • 3
    • 1
    Human
    Wirt
    • 35
    • 4
    Kaninchen
    Klonalität
    • 37
    • 2
    Polyklonal
    Konjugat
    • 18
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GSTa2 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 24
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This GSTA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GSTA2.
    Klon
    RB24006
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product GSTa2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Huang, Guo, Li, Zhang: "Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes." in: Scientific reports, Vol. 7, pp. 40716, (2018) (PubMed).

    Li, Yuan, Li, Liu, Hua, Lu, Zhang: "Direct differentiation of homogeneous human adipose stem cells into functional hepatocytes by mimicking liver embryogenesis." in: Journal of cellular physiology, Vol. 229, Issue 6, pp. 801-12, (2014) (PubMed).

  • Target
    GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
    Andere Bezeichnung
    GSTA2 (GSTa2 Produkte)
    Synonyme
    GSTA1 antikoerper, GST2 antikoerper, GSTA2-2 antikoerper, GTA2 antikoerper, GTH2 antikoerper, Gsta1 antikoerper, Gst2-2 antikoerper, Gstc-2 antikoerper, Gstc2 antikoerper, glutathione S-transferase alpha 2 antikoerper, glutathione S-transferase antikoerper, glutathione S-transferase, alpha 2 (Yc2) antikoerper, GSTA2 antikoerper, Gsta2 antikoerper
    Hintergrund
    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
    Molekulargewicht
    25664
    Gen-ID
    2939
    NCBI Accession
    NP_000837
    UniProt
    P09210
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