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COX6A2 Antikörper (AA 37-66)

COX6A2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB23260 unconjugated
Produktnummer ABIN653569
  • Target Alle COX6A2 Antikörper anzeigen
    COX6A2 (Cytochrome C Oxidase Subunit VIa Polypeptide 2 (COX6A2))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    AA 37-66
    Reaktivität
    • 24
    • 9
    • 1
    • 1
    Human
    Wirt
    • 24
    Kaninchen
    Klonalität
    • 24
    Polyklonal
    Konjugat
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COX6A2 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This COX6A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the Central region of human COX6A2.
    Klon
    RB23260
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. IHC-P: 1:25
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Boczonadi, Giunta, Lane, Tulinius, Schara, Horvath: "Investigating the role of the physiological isoform switch of cytochrome c oxidase subunits in reversible mitochondrial disease." in: The international journal of biochemistry & cell biology, (2015) (PubMed).

  • Target
    COX6A2 (Cytochrome C Oxidase Subunit VIa Polypeptide 2 (COX6A2))
    Andere Bezeichnung
    COX6A2 (COX6A2 Produkte)
    Synonyme
    COX6AH antikoerper, COXVIAH antikoerper, CoxVIaH antikoerper, VIaH antikoerper, cytochrome c oxidase subunit 6A2 antikoerper, cytochrome c oxidase subunit VIa polypeptide 2 antikoerper, COX6A2 antikoerper, Cox6a2 antikoerper
    Hintergrund
    Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66 % amino acid sequence identity.
    Molekulargewicht
    10815
    Gen-ID
    1339
    NCBI Accession
    NP_005196
    UniProt
    Q02221
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