AANAT Antikörper (N-Term)

Produktnummer ABIN653578

Produktdetails anti-AANAT Antikörper

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Bindungsspezifität: AA 27-54, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AANAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AANAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human AANAT.

Klon: RB23834

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu AANAT

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Andere Bezeichnung: AANAT (AANAT Produkte)

Synonyme: DSPS antikoerper, SNAT antikoerper, AA-NAT antikoerper, Nat4 antikoerper, Nat-2 antikoerper, Snat antikoerper, aralkylamine N-acetyltransferase antikoerper, arylalkylamine N-acetyltransferase antikoerper, AANAT antikoerper, Aanat antikoerper

Hintergrund: AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.

Molekulargewicht: 23344

Gen-ID: 15

NCBI Accession: NP_001079, NP_001160051

UniProt: Q16613

Pathways: Photoperiodism