This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This NEIL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human NEIL1.
FPG1 antikoerper, NEI1 antikoerper, hFPG1 antikoerper, 2810450N13Rik antikoerper, Nei1 antikoerper, nei-like DNA glycosylase 1 antikoerper, nei like DNA glycosylase 1 antikoerper, nei endonuclease VIII-like 1 (E. coli) antikoerper, Neil1 antikoerper, NEIL1 antikoerper
Hintergrund
NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).