This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TMEM173 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-340 amino acids from the C-terminal region of human TMEM173.
ERIS antikoerper, MITA antikoerper, MPYS antikoerper, NET23 antikoerper, STING antikoerper, 2610307O08Rik antikoerper, Mita antikoerper, RGD1562552 antikoerper, transmembrane protein 173 antikoerper, TMEM173 antikoerper, Tmem173 antikoerper
Hintergrund
Acts as a facilitator of innate immune signaling. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.