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HDAC2 Antikörper (AA 410-439)

Name: HDAC2 Antikörper (AA 410-439)
SKU: ABIN653718
Price: 445.5 EUR
Availability: InStock

HDAC2 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB24526 unconjugated

HDAC2 Antibody (Center) (ABIN653718 and ABIN2843029) western blot analysis in SH-SY5Y cell line lysates (35 μg/lane). (HDAC2 Antikörper (AA 410-439))

HDAC2 Antibody (Center) (ABIN653718 and ABIN2843029) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram). (HDAC2 Antikörper (AA 410-439))

FACS

Fluorescent confocal image of Hela cell stained with HDAC2 Antibody (Center) (ABIN653718 and ABIN2843029). (HDAC2 Antikörper (AA 410-439))

HDAC2 Antibody (Center) (ABIN653718 and ABIN2843029) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. (HDAC2 Antikörper (AA 410-439))

IHC (p)

4 Abbildungen

(1 reference)

Produktnummer ABIN653718

Datenblatt (PDF)

Target Alle HDAC2 Antikörper anzeigen

HDAC2 (Histone Deacetylase 2 (HDAC2))
Bindungsspezifität
29

15

13

7

7

6

6

5

4

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 410-439
Reaktivität
121

87

61

12

5

4

4

4

4

4

3

1

1
Human
Wirt
107

11

3

1
Kaninchen
Passende Sekundärantikörper
Klonalität
101

21
Polyklonal
Konjugat
64

6

5

5

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2
Dieser HDAC2 Antikörper ist unkonjugiert
Applikation
69

43

38

31

28

27

22

17

16

12

6

4

3

2

1

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie

C, M

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This HDAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the Central region of human HDAC2.

Klon

RB24526

Isotyp

Ig Fraction

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anti-Histone Deacetylase 2 (HDAC2) (pSer394) antibody
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anti-Histone Deacetylase 2 (HDAC2) (AA 217-327) antibody
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Applikationshinweise

IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Leucker, Nomura, Kim, Bhatta, Wang, Wecker, Jandu, Santhanam, Berkowitz, Romer, Pandey: "Cystathionine γ-lyase protects vascular endothelium: a role for inhibition of histone deacetylase 6." in: American journal of physiology. Heart and circulatory physiology, Vol. 312, Issue 4, pp. H711-H720, (2017) (PubMed).
Target

HDAC2 (Histone Deacetylase 2 (HDAC2))

Andere Bezeichnung

HDAC2 (HDAC2 Produkte)

Synonyme

HD2 antikoerper, RPD3 antikoerper, YAF1 antikoerper, D10Wsu179e antikoerper, Yy1bp antikoerper, mRPD3 antikoerper, HISTONE DEACETYLASE antikoerper, T1N24.9 antikoerper, T1N24_9 antikoerper, histone deacetylase 2 antikoerper, histone deacetylase 2 antikoerper, histone deacetylase 2 S homeolog antikoerper, HDAC2 antikoerper, Hdac2 antikoerper, hdac2.S antikoerper, HDA2 antikoerper

Hintergrund

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events.

Molekulargewicht

55364

Gen-ID

3066

NCBI Accession

NP_001518

UniProt

Q92769

Pathways

Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion