This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This FCRL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-507 amino acids from the C-terminal region of human FCRL4.
CD307d antikoerper, FCRH4 antikoerper, IGFP2 antikoerper, IRTA1 antikoerper, FCRL4 antikoerper, Fc receptor like 4 antikoerper, Fc receptor-like 4 antikoerper, Fc receptor-like 4 L homeolog antikoerper, FCRL4 antikoerper, fcrl4 antikoerper, fcrl4.L antikoerper
Hintergrund
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.