PYCR1 Antikörper (C-Term)
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- Target Alle PYCR1 Antikörper anzeigen
- PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))
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Bindungsspezifität
- AA 291-319, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PYCR1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PYCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human PYCR1.
- Klon
- RB24671
- Isotyp
- IgG
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- Applikationshinweise
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer." in: Medical oncology (Northwood, London, England), Vol. 34, Issue 2, pp. 27, (2017) (PubMed).
: "
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Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer." in: Medical oncology (Northwood, London, England), Vol. 34, Issue 2, pp. 27, (2017) (PubMed).
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- Target
- PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))
- Andere Bezeichnung
- PYCR1 (PYCR1 Produkte)
- Hintergrund
- This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion.
- Molekulargewicht
- 33361
- Gen-ID
- 5831
- NCBI Accession
- NP_001269209, NP_001269210, NP_008838, NP_722546
- UniProt
- P32322
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