Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
Pig
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MUTED antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the Central region of human MUTED.
BLOS5 antikoerper, MU antikoerper, MUTED antikoerper, muted antikoerper, 1810074A19Rik antikoerper, Muted antikoerper, mu antikoerper, biogenesis of lysosomal organelles complex 1 subunit 5 antikoerper, biogenesis of lysosomal organelles complex 1 subunit 5 L homeolog antikoerper, biogenesis of lysosomal organelles complex-1, subunit 5, muted antikoerper, BLOC1S5 antikoerper, bloc1s5.L antikoerper, Bloc1s5 antikoerper
Hintergrund
This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.