Claudin 7 Antikörper (C-Term)

Produktnummer ABIN654139

Produktdetails anti-Claudin 7 Antikörper

Target: Claudin 7 (CLDN7)

Bindungsspezifität: AA 172-201, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CLDN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-201 amino acids from the C-terminal region of human CLDN7.

Klon: RB23672

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Claudin 7

Target: Claudin 7 (CLDN7)

Andere Bezeichnung: CLDN7 (CLDN7 Produkte)

Synonyme: cb388 antikoerper, claudin7 antikoerper, cldn7 antikoerper, wu:fd19f08 antikoerper, MGC53400 antikoerper, MGC75689 antikoerper, CLDN7 antikoerper, CEPTRL2 antikoerper, CLDN-7 antikoerper, CPETRL2 antikoerper, Hs.84359 antikoerper, claudin-1 antikoerper, claudin 7b antikoerper, claudin 7 L homeolog antikoerper, claudin 7 antikoerper, cldn7b antikoerper, cldn7.L antikoerper, cldn7 antikoerper, CLDN7 antikoerper, Cldn7 antikoerper

Hintergrund: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.

Molekulargewicht: 22418

Gen-ID: 1366

NCBI Accession: NP_001171951, NP_001171952, NP_001298

UniProt: O95471

Pathways: Hepatitis C