MED25 Antikörper (AA 112-140)
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- Target Alle MED25 Antikörper anzeigen
- MED25 (Mediator Complex Subunit 25 (MED25))
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Bindungsspezifität
- AA 112-140
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MED25 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- B
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This MED25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids of human MED25.
- Klon
- RB24225
- Isotyp
- IgG
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- Applikationshinweise
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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MED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells." in: PLoS ONE, Vol. 7, Issue 8, pp. e44007, (2013) (PubMed).
: "
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MED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells." in: PLoS ONE, Vol. 7, Issue 8, pp. e44007, (2013) (PubMed).
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- Target
- MED25 (Mediator Complex Subunit 25 (MED25))
- Andere Bezeichnung
- MED25 (MED25 Produkte)
- Hintergrund
- This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq].
- Molekulargewicht
- 78171
- Gen-ID
- 81857
- NCBI Accession
- NP_112235
- UniProt
- Q71SY5
- Pathways
- Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response
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