This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This NOS1AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-466 amino acids from the Central region of human NOS1AP.
MGC78853 antikoerper, Capon antikoerper, MGC145362 antikoerper, 6330408P19Rik antikoerper, CAPON antikoerper, nitric oxide synthase 1 adaptor protein antikoerper, nitric oxide synthase 1 adaptor protein L homeolog antikoerper, nitric oxide synthase 1 (neuronal) adaptor protein a antikoerper, carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein antikoerper, chromosome 18 C1orf226 homolog antikoerper, nitric oxide synthase 1 (neuronal) adaptor protein antikoerper, NOS1AP antikoerper, nos1ap.L antikoerper, nos1apa antikoerper, LOC609484 antikoerper, nos1ap antikoerper, LOC100058633 antikoerper, C18H1orf226 antikoerper, Nos1ap antikoerper
Hintergrund
This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.