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DENND1B Antikörper (N-Term)

DENND1B Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB28056 unconjugated
Produktnummer ABIN654339
  • Target Alle DENND1B Antikörper anzeigen
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 39-68, N-Term
    Reaktivität
    • 31
    • 20
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 1
    Kaninchen
    Klonalität
    • 46
    Polyklonal
    Konjugat
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DENND1B Antikörper ist unkonjugiert
    Applikation
    • 39
    • 16
    • 15
    • 13
    • 13
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This DENND1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human DENND1B.
    Klon
    RB28056
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:500. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    Andere Bezeichnung
    DENND1B (DENND1B Produkte)
    Synonyme
    C1ORF18 antikoerper, C1orf218 antikoerper, FAM31B antikoerper, 4632404N19Rik antikoerper, 4930467M19Rik antikoerper, 6820401H01Rik antikoerper, F730008N07Rik antikoerper, Fam31b antikoerper, si:ch211-195i21.1 antikoerper, DENN domain containing 1B antikoerper, DENN/MADD domain containing 1B antikoerper, DENND1B antikoerper, dennd1b antikoerper, Dennd1b antikoerper
    Hintergrund
    Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).
    Molekulargewicht
    86552
    Gen-ID
    163486
    NCBI Accession
    NP_001182144, NP_001182145, NP_659414
    UniProt
    Q6P3S1
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