Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This AIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-36 amino acids from the N-terminal region of human AIF1.
IBA1
Reaktivität: Human
IHC, StM
Wirt: Maus
Monoclonal
AIF1-1909
unconjugated
Applikationshinweise
WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Ye, Miao, Lu, Xia, Chen, Zhang, Wu, He, Qiang, Zhou: "Allograft inflammatory factor-1 is an independent prognostic indicator that regulates β-catenin in gastric cancer." in: Oncology reports, Vol. 31, Issue 2, pp. 828-34, (2013) (PubMed).
DiFranco, Gupta, Galusha, Perez, Nguyen, Fineza, Kachlany: "Leukotoxin (Leukothera®) targets active leukocyte function antigen-1 (LFA-1) protein and triggers a lysosomal mediated cell death pathway." in: The Journal of biological chemistry, Vol. 287, Issue 21, pp. 17618-27, (2012) (PubMed).
AIF1 is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma.