This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This INPP5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 950-979 amino acids from the C-terminal region of human INPP5B.
75kDa antikoerper, AW260155 antikoerper, INPP5P antikoerper, 5PTase antikoerper, inositol polyphosphate-5-phosphatase B antikoerper, type II inositol 1,4,5-trisphosphate 5-phosphatase-like antikoerper, inositol polyphosphate-5-phosphatase B L homeolog antikoerper, inositol polyphosphate 5-phosphatase OCRL-1 antikoerper, INPP5B antikoerper, LOC100224437 antikoerper, inpp5b.L antikoerper, LOC100159919 antikoerper, Inpp5b antikoerper
Hintergrund
Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq].