This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PURG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the C-terminal region of human PURG.
PURG-A antikoerper, PURG-B antikoerper, 4930486B15Rik antikoerper, purine rich element binding protein G antikoerper, purine-rich element binding protein G antikoerper, PURG antikoerper, purg antikoerper, Purg antikoerper
Hintergrund
The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. PURG lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. Two transcript variants encoding different isoforms have been found for this gene.