Complement C2 Antikörper (N-Term)

Produktnummer ABIN654619

Produktdetails anti-Complement C2 Antikörper

Target: Complement C2

Bindungsspezifität: AA 147-176, N-Term

Reaktivität: Human, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Complement C2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-180 amino acids from the N-terminal region of human C2.

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 AA from the N-terminal region of human C2.

Klon: RB18356

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB = 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.26 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu Complement C2

Target: Complement C2

Andere Bezeichnung: C2 (Complement C2 Produkte)

Synonyme: CO2 antikoerper, complement C2 antikoerper, complement component 2 (within H-2S) antikoerper, C2 antikoerper

Hintergrund: Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.
Synonyms: Complement C2,C2,

Molekulargewicht: 83268 DA

Gen-ID: 717

NCBI Accession: NP_000054

UniProt: P06681