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CASP5 Antikörper (AA 162-191)

CASP5 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB18988 unconjugated
Produktnummer ABIN654898
  • Target Alle CASP5 Antikörper anzeigen
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Bindungsspezifität
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 162-191
    Reaktivität
    • 43
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 40
    • 3
    Kaninchen
    Klonalität
    • 33
    • 10
    Polyklonal
    Konjugat
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser CASP5 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CASP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human CASP5.
    Klon
    RB18988
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CASP5 Primärantikörper
  • Applikationshinweise
    WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Andere Bezeichnung
    CASP5 (CASP5 Produkte)
    Synonyme
    ICE(rel)III antikoerper, ICEREL-III antikoerper, ICH-3 antikoerper, CASP5 antikoerper, caspase 5 antikoerper, caspase-5 antikoerper, CASP5 antikoerper, LOC100437308 antikoerper
    Hintergrund
    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
    Molekulargewicht
    49736
    Gen-ID
    838
    NCBI Accession
    NP_001129581, NP_001129582, NP_001129584, NP_004338
    UniProt
    P51878
    Pathways
    Inflammasome
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