ANAPC5 Antikörper (AA 156-185)

Produktnummer ABIN654927

Produktdetails anti-ANAPC5 Antikörper

Target: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Bindungsspezifität: AA 156-185

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANAPC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ANAPC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human ANAPC5.

Klon: RB24572

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu ANAPC5

Target: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Andere Bezeichnung: ANAPC5 (ANAPC5 Produkte)

Synonyme: APC5 antikoerper, DDBDRAFT_0206386 antikoerper, DDBDRAFT_0234269 antikoerper, DDB_0206386 antikoerper, DDB_0234269 antikoerper, zgc:55800 antikoerper, wu:fb75a09 antikoerper, ANAPC5 antikoerper, MGC89697 antikoerper, 2510006G12Rik antikoerper, AA408751 antikoerper, AA536819 antikoerper, AA986414 antikoerper, Anpc5 antikoerper, F12K11.7 antikoerper, F12K11_7 antikoerper, anaphase promoting complex subunit 5 antikoerper, anaphase-promoting complex subunit 5 antikoerper, anaphase promoting complex subunit 5 L homeolog antikoerper, anaphase-promoting complex subunit antikoerper, anaphase-promoting complex subunit Apc5 antikoerper, ANAPC5 antikoerper, anapc5 antikoerper, LOC100093215 antikoerper, anapc5.L antikoerper, Anapc5 antikoerper, AT1G06590 antikoerper, apc5 antikoerper

Hintergrund: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

Molekulargewicht: 85077

Gen-ID: 51433

NCBI Accession: NP_001131031, NP_057321

UniProt: Q9UJX4

Pathways: M Phase