AIRE Antikörper (AA 64-92)

Produktnummer ABIN655031

Produktdetails anti-AIRE Antikörper

Target: AIRE (Autoimmune Regulator (AIRE))

Bindungsspezifität: AA 64-92

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIRE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AIRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human AIRE.

Klon: RB30050

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu AIRE

Target: AIRE (Autoimmune Regulator (AIRE))

Andere Bezeichnung: AIRE (AIRE Produkte)

Synonyme: AIRE1 antikoerper, APECED antikoerper, APS1 antikoerper, APSI antikoerper, PGA1 antikoerper, autoimmune regulator antikoerper, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antikoerper, AaeL_AAEL013794 antikoerper, CpipJ_CPIJ001208 antikoerper, CpipJ_CPIJ001209 antikoerper, AIRE antikoerper, Aire antikoerper

Hintergrund: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).

Molekulargewicht: 57727

Gen-ID: 326

NCBI Accession: NP_000374

UniProt: O43918

Pathways: Chromatin Binding