IFT88 Antikörper (C-Term)

Produktnummer ABIN655090

Produktdetails anti-IFT88 Antikörper

Target: IFT88 (Intraflagellar Transport 88 Homolog (IFT88))

Bindungsspezifität: AA 791-820, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFT88 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IFT88 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 791-820 amino acids from the C-terminal region of human IFT88.

Klon: RB24875

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-IFT88 Antikörper (ABIN655090)

Xiang, Guo, Cheng, Zhang, Huang, Wang, Ma, Xu: "HDAC6 inhibition suppresses chondrosarcoma by restoring the expression of primary cilia." in: Oncology reports, Vol. 38, Issue 1, pp. 229-236, (2018) (PubMed).

Zhan, Xiang, Guo, Ma: "Basic fibroblast growth factor increases IFT88 expression in chondrocytes." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 6590-6599, (2018) (PubMed).

Xiang, Jiang, Guo, Gong, Yang, Wu, Huang, Cheng, Xu: "Hedgehog pathway inhibitor-4 suppresses malignant properties of chondrosarcoma cells by disturbing tumor ciliogenesis." in: Oncology reports, Vol. 32, Issue 4, pp. 1622-30, (2014) (PubMed).

Details zu IFT88

Target: IFT88 (Intraflagellar Transport 88 Homolog (IFT88))

Andere Bezeichnung: IFT88 (IFT88 Produkte)

Synonyme: 146590_s_at antikoerper, CG12548 antikoerper, CG14465 antikoerper, CG15190 antikoerper, CG4137 antikoerper, Dmel\\CG12548 antikoerper, IFT88 antikoerper, NOMPB antikoerper, OSM-5 antikoerper, Tg737 antikoerper, nomp antikoerper, osm-5 antikoerper, AW552028 antikoerper, Tg737Rpw antikoerper, TgN737Rpw antikoerper, Ttc10 antikoerper, flexo antikoerper, fxo antikoerper, orpk antikoerper, polaris antikoerper, D13S1056E antikoerper, DAF19 antikoerper, TG737 antikoerper, TTC10 antikoerper, hTg737 antikoerper, intraflagellar transport 88 antikoerper, intraflagellar transport 88 homolog antikoerper, intraflagellar transport protein 88 homolog antikoerper, no mechanoreceptor potential B antikoerper, IFT88 antikoerper, ift88 antikoerper, LOC100518926 antikoerper, LOC100640298 antikoerper, LOC100646898 antikoerper, nompB antikoerper, Ift88 antikoerper

Hintergrund: This gene encodes a member of the tetratrico peptide repeat (TPR) family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq].

Gen-ID: 8100

NCBI Accession: NP_006522, NP_783195

UniProt: Q13099

Pathways: Hedgehog Signalweg, Sensory Perception of Sound