This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This KSR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 603-638 amino acids from the C-terminal region of human KSR2.
kinase suppressor of ras 2 antikoerper, KSR2 antikoerper, Ksr2 antikoerper
Hintergrund
Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.