Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

SP1 Antikörper (C-Term)

Name: SP1 Antikörper (C-Term)
SKU: ABIN655398
Price: 445.5 EUR
Availability: InStock

SP1 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB17350 unconjugated

Anti-SP1 Antibody (C-term ) at 1:500 dilution + Hela whole cell lysate Lysates/proteins at 20 μg per lane. (SP1 Antikörper (C-Term))

SP1 Antibody (C-term ) (ABIN655398 and ABIN2844945) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram). (SP1 Antikörper (C-Term))

FACS

Confocal immunofluorescent analysis of SP1 Antibody (C-term ) (ABIN655398 and ABIN2844945) with WiDr cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (SP1 Antikörper (C-Term))

SP1 Antibody (C-term ) (ABIN655398 and ABIN2844945) western blot analysis in K562 cell line lysates (35 μg/lane). (SP1 Antikörper (C-Term))

SP1 Antibody (C-term ) (ABIN655398 and ABIN2844945) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. (SP1 Antikörper (C-Term))

IHC (p)

5 Abbildungen

(1 reference)

Produktnummer ABIN655398

Datenblatt (PDF)

Target Alle SP1 Antikörper anzeigen

SP1 (Sp1 Transcription Factor (SP1))
Bindungsspezifität
21

14

12

7

7

6

6

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 677-707, C-Term
Reaktivität
97

67

46

11

8

7

6

5

5

5

4

2

2

2

1
Human
Wirt
99

13

3
Kaninchen
Passende Sekundärantikörper
Klonalität
94

21
Polyklonal
Konjugat
70

6

3

3

3

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser SP1 Antikörper ist unkonjugiert
Applikation
93

49

47

40

20

15

14

14

13

7

3

3

3

2

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie

M, Rat

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This SP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 677-707 amino acids from the C-terminal region of human SP1.

Klon

RB17350

Isotyp

Ig Fraction
anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibody
SP1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1A5 unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 522-618) antibody
SP1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4B11 unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibody
SP1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 4H6 unconjugated

anti-Sp1 Transcription Factor (SP1) (C-Term) antibody
SP1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Sp1 Transcription Factor (SP1) (pThr453) antibody
SP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Sp1 Transcription Factor (SP1) antibody
SP1 Reaktivität: Human WB, IHC, IF, ChIP Wirt: Kaninchen Monoclonal unconjugated

anti-Sp1 Transcription Factor (SP1) (pThr739) antibody
SP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 420-620) antibody
SP1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 89-199) antibody
SP1 Reaktivität: Human, Maus WB, ELISA, IF Wirt: Maus Monoclonal 4H6 unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 677-707) antibody
SP1 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

IF: 1:10~50. WB: 1:500. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Zhang, Wang, Qin, Liu, Sun, Liu, Kuang, Jiang, Zhang: "cis-Acting elements and trans-acting factors in the transcriptional regulation of raf kinase inhibitory protein expression." in: PLoS ONE, Vol. 8, Issue 12, pp. e83097, (2014) (PubMed).
Target

SP1 (Sp1 Transcription Factor (SP1))

Andere Bezeichnung

SP1 (SP1 Produkte)

Synonyme

fc18h09 antikoerper, zgc:85950 antikoerper, wu:fc18h09 antikoerper, SP1 antikoerper, 1110003E12Rik antikoerper, AA450830 antikoerper, AI845540 antikoerper, Sp1-1 antikoerper, sp1 transcription factor antikoerper, Sp1 transcription factor antikoerper, Sp1 transcription factor L homeolog antikoerper, trans-acting transcription factor 1 antikoerper, sp1 antikoerper, SP1 antikoerper, Sp1 antikoerper, sp1.L antikoerper

Hintergrund

Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

Molekulargewicht

80693

Gen-ID

6667

NCBI Accession

NP_001238754, NP_003100, NP_612482

UniProt

P08047

Pathways

Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction