Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
Homologie
B
Aufreinigung
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CREB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-132 amino acids from the Central region of human CREB1.
CREB1
Reaktivität: Human
WB, IHC, ELISA, IF
Wirt: Kaninchen
Monoclonal
3C11
unconjugated
Recombinant Antibody
Applikationshinweise
IF: 1:10~50. WB: 1:1000. WB: 1:2000. FC: 1:25
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Zhang, Wang, Qin, Liu, Sun, Liu, Kuang, Jiang, Zhang: "cis-Acting elements and trans-acting factors in the transcriptional regulation of raf kinase inhibitory protein expression." in: PLoS ONE, Vol. 8, Issue 12, pp. e83097, (2014) (PubMed).
Target
CREB1
(cAMP Responsive Element Binding Protein 1 (CREB1))
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Hintergrund
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.