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Nibrin Antikörper (C-Term)

Name: Nibrin Antikörper (C-Term)
SKU: ABIN655721
Price: 445.5 EUR
Availability: InStock

NBN Reaktivität: Human WB, IF, FACS Wirt: Kaninchen Polyclonal RB19072 unconjugated

NBN Antibody (C-term) (ABIN655721 and ABIN2845169) western blot analysis in NCI-,NCI- cell line lysates (35 μg/lane). (Nibrin Antikörper (C-Term))

NBN Antibody (C-term) (ABIN655721 and ABIN2845169) flow cytometric analysis of NCI- cells (right histogram) compared to a negative control cell (left histogram). (Nibrin Antikörper (C-Term))

FACS

Confocal immunofluorescent analysis of NBN Antibody (C-term) (ABIN655721 and ABIN2845169) with Hela cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). (Nibrin Antikörper (C-Term))

3 Abbildungen

Produktnummer ABIN655721

Datenblatt (PDF)

Target Alle Nibrin (NBN) Antikörper anzeigen

Nibrin (NBN)
Bindungsspezifität
37

15

11

7

7

5

5

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 602-630, C-Term
Reaktivität
100

60

36

2

1

1

1

1
Human
Wirt
117

15
Kaninchen
Passende Sekundärantikörper
Klonalität
108

24
Polyklonal
Konjugat
66

8

5

4

4

4

4

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2
Dieser Nibrin Antikörper ist unkonjugiert
Applikation
103

47

27

27

26

26

23

16

9

8

6

4

2

2

1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This NBN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 602-630 amino acids from the C-terminal region of human NBN.

Klon

RB19072

Isotyp

Ig Fraction

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NBN Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 6E11 unconjugated

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NBN Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated

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NBN Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3E4 unconjugated

anti-Nibrin (NBN) antibody
KO Validated NBN Reaktivität: Human WB, IF, ICC, IP Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

IF: 1:10~50. WB: 1:1000. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

Nibrin (NBN)

Andere Bezeichnung

NBN (NBN Produkte)

Synonyme

NBN antikoerper, AT-V1 antikoerper, AT-V2 antikoerper, ATV antikoerper, NBS antikoerper, NBS1 antikoerper, P95 antikoerper, Nbs1 antikoerper, im:6911679 antikoerper, zgc:194152 antikoerper, nibrin antikoerper, NBN antikoerper, nbn antikoerper, Nbn antikoerper

Hintergrund

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Molekulargewicht

84959

Gen-ID

4683

NCBI Accession

NP_002476

UniProt

O60934

Pathways

DNA Reparatur, Production of Molecular Mediator of Immune Response