RGD1306411 antikoerper, si:ch211-79l17.3 antikoerper, WT1 interacting protein antikoerper, Wilms tumor 1 interacting protein antikoerper, WT1 interacting protein L homeolog antikoerper, WT1-interacting protein antikoerper, Wtip antikoerper, WTIP antikoerper, wtip antikoerper, wtip.L antikoerper
Hintergrund
WTIP may monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1-dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype (By similarity).