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IRF9 Antikörper (AA 75-104)

IRF9 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB19229 unconjugated
Produktnummer ABIN655818
  • Target Alle IRF9 Antikörper anzeigen
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Bindungsspezifität
    • 15
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 75-104
    Reaktivität
    • 47
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 41
    • 7
    • 1
    Kaninchen
    Klonalität
    • 43
    • 5
    Polyklonal
    Konjugat
    • 24
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IRF9 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 15
    • 13
    • 13
    • 9
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This IRF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids of human IRF9.
    Klon
    RB19229
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product IRF9 Primärantikörper
  • Applikationshinweise
    IF: 1:10~50. WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Andere Bezeichnung
    IRF9 (IRF9 Produkte)
    Synonyme
    IRF-9 antikoerper, ISGF3 antikoerper, ISGF3G antikoerper, p48 antikoerper, zgc:92097 antikoerper, Irf-9 antikoerper, Isgf3g antikoerper, interferon regulatory factor 9 antikoerper, IRF9 antikoerper, irf9 antikoerper, Irf9 antikoerper
    Hintergrund
    IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
    Molekulargewicht
    43696
    Gen-ID
    10379
    NCBI Accession
    NP_006075
    UniProt
    Q00978
    Pathways
    JAK-STAT Signalweg, Interferon-gamma Pathway, Hepatitis C
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