DDIT3 Antikörper (C-Term)

Produktnummer ABIN655895

Produktdetails anti-DDIT3 Antikörper

Target: DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

Bindungsspezifität: AA 120-149, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDIT3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Homologie: B, Ha

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DDIT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the C-terminal region of human DDIT3.

Klon: RB13788

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:2000. WB: 1:2000. WB: 1:1000. FC: 1:25. FC: 1:25. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu DDIT3

Target: DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

Andere Bezeichnung: DDIT3 (DDIT3 Produkte)

Synonyme: chop antikoerper, Xchop antikoerper, cebpz antikoerper, chop10 antikoerper, gadd153 antikoerper, CHOP-10 antikoerper, CHOP10 antikoerper, CHOP antikoerper, Chop10 antikoerper, Gadd153 antikoerper, CEBPZ antikoerper, GADD153 antikoerper, DNA damage inducible transcript 3 antikoerper, DNA-damage inducible transcript 3 antikoerper, DNA damage inducible transcript 3 L homeolog antikoerper, ddit3 antikoerper, Ddit3 antikoerper, DDIT3 antikoerper, ddit3.L antikoerper

Hintergrund: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

Molekulargewicht: 19175

Gen-ID: 1649

NCBI Accession: NP_001181982, NP_001181983, NP_001181984, NP_001181986, NP_004074

UniProt: P35638

Pathways: Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis