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PDCD1LG2 Antikörper (APC)

PDCD1LG2 Reaktivität: Human FACS Wirt: Maus Monoclonal 24F-10C12 APC
Produktnummer ABIN6559835
  • Target Alle PDCD1LG2 Antikörper anzeigen
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    Reaktivität
    • 75
    • 31
    • 10
    • 3
    Human
    Wirt
    • 47
    • 31
    • 18
    • 1
    Maus
    Klonalität
    • 49
    • 45
    • 1
    Monoklonal
    Konjugat
    • 52
    • 11
    • 10
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PDCD1LG2 Antikörper ist konjugiert mit APC
    Applikation
    • 49
    • 46
    • 38
    • 30
    • 16
    • 11
    • 10
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody 24F.10C12 recognizes an extracellular epitope of CD273 / PD-L2 (also known as B7-DC), a 25 kDa type I transmembrane protein expressed by dendritic cells, activated monocytes and T cells, heart, first trimester placenta, lung and liver, as well as in Hodgkin´s lymphoma cells and primary mediastinal B cell lymphoma (PMBL).
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    human CD273 cDNA
    Klon
    24F-10C12
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product PDCD1LG2 Primärantikörper
  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    Andere Bezeichnung
    CD273 / PD-L2 (PDCD1LG2 Produkte)
    Synonyme
    PDL2 antikoerper, B7DC antikoerper, Btdc antikoerper, CD273 antikoerper, PD-L2 antikoerper, PDCD1L2 antikoerper, bA574F11.2 antikoerper, B7-DC antikoerper, F730015O22Rik antikoerper, programmed cell death 1 ligand 2 antikoerper, PDCD1LG2 antikoerper, Pdcd1lg2 antikoerper
    Hintergrund
    Programmed cell death 1 ligand 2,CD273 / PD-L2 (programmed death ligand-1), also known as B7-DC, is a member of the B7 family of regulatory proteins. It costimulates the proliferation of T cells, and mediates IFN gamma production. Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses. When interacting with CD279, it can act as a coinhibitor of the T cell function. CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas.,PDCD1LG2, B7DC, Btdc, PDL2, PDCD1L2, bA574F11.2, Butyrophilin, B7-DC,
    Gen-ID
    80380
    UniProt
    Q9BQ51
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