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LEF1 Antikörper (N-Term)

LEF1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal RB31989 unconjugated
Produktnummer ABIN655987
  • Target Alle LEF1 Antikörper anzeigen
    LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-37, N-Term
    Reaktivität
    • 78
    • 19
    • 13
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 49
    • 24
    • 4
    • 1
    Kaninchen
    Klonalität
    • 53
    • 25
    Polyklonal
    Konjugat
    • 58
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LEF1 Antikörper ist unkonjugiert
    Applikation
    • 64
    • 35
    • 12
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Homologie
    M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This LEF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from the N-terminal region of human LEF1.
    Klon
    RB31989
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product LEF1 Primärantikörper
  • Applikationshinweise
    IF: 1:10~50. WB: 1:2000. WB: 1:2000. WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Yao, Li, Liang, Lu, Zhu, Liu, Zhang, Yuan, Wang: "Methylprednisolone suppresses the Wnt signaling pathway in chronic lymphocytic leukemia cell line MEC-1 regulated by LEF-1 expression." in: International journal of clinical and experimental pathology, Vol. 8, Issue 7, pp. 7921-8, (2015) (PubMed).

  • Target
    LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
    Andere Bezeichnung
    LEF1 (LEF1 Produkte)
    Synonyme
    LEF1 antikoerper, 3000002B05 antikoerper, AI451430 antikoerper, Lef-1 antikoerper, LEF-1 antikoerper, TCF10 antikoerper, TCF1ALPHA antikoerper, TCF7L3 antikoerper, lymphoid enhancer binding factor 1 antikoerper, lymphoid enhancer-binding factor 1 antikoerper, lymphoid enhancer factor XLEF-1B antikoerper, LEF1 antikoerper, lef1 antikoerper, Lef1 antikoerper
    Hintergrund
    This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
    Molekulargewicht
    44201
    Gen-ID
    51176
    NCBI Accession
    NP_001124185, NP_001124186, NP_001159591, NP_057353
    UniProt
    Q9UJU2
    Pathways
    WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
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