KDM3B Antikörper (AA 869-897)

Produktnummer ABIN656008

Produktdetails anti-KDM3B Antikörper

Target: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Bindungsspezifität: AA 869-897

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Homologie: M

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This JHDM2b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 869-897 amino acids from the Central region of human JHDM2b.

Klon: RB14344

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu KDM3B

Target: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Andere Bezeichnung: JHDM2b (KDM3B Produkte)

Synonyme: KDM3B antikoerper, JMJD1B antikoerper, 5830462I21Rik antikoerper, JHDM2B antikoerper, Jmjd1b antikoerper, mKIAA1082 antikoerper, 5qNCA antikoerper, C5orf7 antikoerper, NET22 antikoerper, lysine demethylase 3B antikoerper, lysine (K)-specific demethylase 3B antikoerper, lysine-specific demethylase 3B antikoerper, KDM3B lysine (K)-specific demethylase 3B antikoerper, KDM3B antikoerper, LOC100540242 antikoerper, kdm3b antikoerper, Kdm3b antikoerper

Hintergrund: Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.

Molekulargewicht: 191581

Gen-ID: 51780

NCBI Accession: NP_057688

UniProt: Q7LBC6

Pathways: Warburg Effekt