PCDHAC2 Antikörper (AA 616-644)

Produktnummer ABIN656091

Produktdetails anti-PCDHAC2 Antikörper

Target: PCDHAC2 (Protocadherin alpha Subfamily C, 2 (PCDHAC2))

Bindungsspezifität: AA 616-644

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHAC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 616-644 amino acids from the Central region of human PCDHAC2.

Klon: RB31967

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PCDHAC2

Target: PCDHAC2 (Protocadherin alpha Subfamily C, 2 (PCDHAC2))

Andere Bezeichnung: PCDHAC2 (PCDHAC2 Produkte)

Synonyme: PCDH-ALPHA-C2 antikoerper, CNRc2 antikoerper, rCNRvc2 antikoerper, CNRC02 antikoerper, PCHD antikoerper, protocadherin alpha subfamily C, 2 antikoerper, PCDHAC2 antikoerper, Pcdhac2 antikoerper, pcdhac2 antikoerper

Hintergrund: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Molekulargewicht: 109450

Gen-ID: 56134

NCBI Accession: NP_061722, NP_114089

UniProt: Q9Y5I4