CHRNA10 Antikörper (AA 179-206)

Produktnummer ABIN656120

Produktdetails anti-CHRNA10 Antikörper

Target: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Bindungsspezifität: AA 179-206

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CHRNA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the Central region of human CHRNA10.

Klon: RB32240

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CHRNA10

Target: CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))

Andere Bezeichnung: CHRNA10 (CHRNA10 Produkte)

Synonyme: si:dkey-24p1.3 antikoerper, ALPHA 10 nAChR antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 10 antikoerper, cholinergic receptor nicotinic alpha 10 subunit antikoerper, cholinergic receptor, nicotinic, alpha 10a antikoerper, neuronal acetylcholine receptor subunit alpha-10 antikoerper, cholinergic receptor, nicotinic, alpha 10 (neuronal) antikoerper, Chrna10 antikoerper, CHRNA10 antikoerper, chrna10a antikoerper, LOC100344381 antikoerper

Hintergrund: CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Molekulargewicht: 49705

Gen-ID: 57053

NCBI Accession: NP_065135

UniProt: Q9GZZ6

Pathways: Sensory Perception of Sound, Synaptic Membrane