MED14 Antikörper (AA 586-615)

Produktnummer ABIN656136

Produktdetails anti-MED14 Antikörper

Target: MED14 (Mediator Complex Subunit 14 (MED14))

Bindungsspezifität: AA 586-615

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MED14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-615 amino acids from the Central region of human MED14.

Klon: RB20179

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:4000. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: MED14 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu MED14

Target: MED14 (Mediator Complex Subunit 14 (MED14))

Andere Bezeichnung: MED14 (MED14 Produkte)

Synonyme: CG12031 antikoerper, Dmel\\CG12031 antikoerper, Med14 antikoerper, Trap170 antikoerper, dTRAP170 antikoerper, p160 antikoerper, EXLM1 antikoerper, crsp150 antikoerper, crsp2 antikoerper, trap170 antikoerper, wu:fd21c05 antikoerper, wu:fk28h11 antikoerper, CRSP2 antikoerper, NV18605 antikoerper, CRSP150 antikoerper, CSRP antikoerper, CXorf4 antikoerper, DRIP150 antikoerper, RGR1 antikoerper, TRAP170 antikoerper, 9930001L01Rik antikoerper, AU041628 antikoerper, Crsp2 antikoerper, ENSMUSG00000073278 antikoerper, Gm641 antikoerper, ORF1 antikoerper, RGD1560170 antikoerper, Mediator complex subunit 14 antikoerper, mediator complex subunit 14 antikoerper, mediator of RNA polymerase II transcription subunit 14 antikoerper, transcriptional regulation antikoerper, MED14 antikoerper, med14 antikoerper, LOC100113592 antikoerper, Med14 antikoerper, RGR1 antikoerper

Hintergrund: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.

Molekulargewicht: 160607

Gen-ID: 9282

NCBI Accession: NP_004220

UniProt: O60244

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha