DCC Antikörper (AA 643-670)
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- Target Alle DCC Antikörper anzeigen
- DCC (Deleted in Colorectal Carcinoma (DCC))
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Bindungsspezifität
- AA 643-670
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DCC Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This DCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 643-670 amino acids from the Central region of human DCC.
- Klon
- RB32203
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product DCC Primärantikörper
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- Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- DCC Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- DCC (Deleted in Colorectal Carcinoma (DCC))
- Andere Bezeichnung
- DCC (DCC Produkte)
- Synonyme
- CRC18 antikoerper, CRCR1 antikoerper, IGDCC1 antikoerper, MRMV1 antikoerper, DCC antikoerper, zdcc antikoerper, C030036D22Rik antikoerper, Igdcc1 antikoerper, xdcc antikoerper, XDCCa antikoerper, dcca-A antikoerper, Dcc antikoerper, DCC netrin 1 receptor antikoerper, deleted in colorectal carcinoma antikoerper, netrin receptor DCC antikoerper, DCC antikoerper, dcc antikoerper, Dcc antikoerper, LOC100712666 antikoerper
- Hintergrund
- This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.
- Molekulargewicht
- 158457
- Gen-ID
- 1630
- NCBI Accession
- NP_005206
- UniProt
- P43146
- Pathways
- Regulation of Cell Size
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