PITRM1 Antikörper (AA 490-518)

Produktnummer ABIN656324

Produktdetails anti-PITRM1 Antikörper

Target: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Bindungsspezifität: AA 490-518

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PITRM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1.

Klon: RB31351

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PITRM1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu PITRM1

Target: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Andere Bezeichnung: PITRM1 (PITRM1 Produkte)

Synonyme: MP1 antikoerper, PreP antikoerper, 2310012C15Rik antikoerper, AA410010 antikoerper, MP-1 antikoerper, Ntup1 antikoerper, mKIAA1104 antikoerper, PITRM1 antikoerper, wu:fa03d09 antikoerper, zgc:55469 antikoerper, pitrilysin metallopeptidase 1 antikoerper, pitrilysin metallepetidase 1 antikoerper, pitrilysin metallopeptidase 1 L homeolog antikoerper, PITRM1 antikoerper, Pitrm1 antikoerper, pitrm1.L antikoerper, pitrm1 antikoerper

Hintergrund: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

Molekulargewicht: 117413

Gen-ID: 10531

NCBI Accession: NP_001229236, NP_001229238, NP_055704

UniProt: Q5JRX3

Pathways: PI3K-Akt Signalweg, SARS-CoV-2 Protein Interaktom