This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CHMP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CHMP6.
chmp6 antikoerper, vps20 antikoerper, 2400004G01Rik antikoerper, VPS20 antikoerper, RGD1565325 antikoerper, chmp6l antikoerper, flj11749l antikoerper, wu:fb79d02 antikoerper, zgc:110067 antikoerper, charged multivesicular body protein 6 antikoerper, charged multivesicular body protein 6 L homeolog antikoerper, charged multivesicular body protein 6 S homeolog antikoerper, charged multivesicular body protein 6b antikoerper, LOC100280982 antikoerper, chmp6.L antikoerper, chmp6.S antikoerper, CHMP6 antikoerper, chmp6 antikoerper, Tsp_08316 antikoerper, Chmp6 antikoerper, chmp6b antikoerper
Hintergrund
CHMP6 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).