TMEM43 Antikörper (AA 195-223)

Produktnummer ABIN656549

Produktdetails anti-TMEM43 Antikörper

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Bindungsspezifität: AA 195-223

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM43 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TMEM43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human TMEM43.

Klon: RB32139

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TMEM43 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu TMEM43

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Andere Bezeichnung: TMEM43 (TMEM43 Produkte)

Synonyme: zgc:85946 antikoerper, ARVC5 antikoerper, ARVD5 antikoerper, EDMD7 antikoerper, LUMA antikoerper, 1200015A22Rik antikoerper, transmembrane protein 43 antikoerper, TMEM43 antikoerper, tmem43 antikoerper, Tmem43 antikoerper

Hintergrund: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Molekulargewicht: 44876

Gen-ID: 79188

NCBI Accession: NP_077310

UniProt: Q9BTV4